Abstracts
Résumé
L’adversité au cours du jeune âge est connue pour augmenter le risque de développer des problèmes de santé mentale à l’âge adulte. Récemment, des mécanismes épigénétiques ont été identifiés comme représentant une interface sur laquelle l’environnement agit pour induire des changements comportementaux. Ces changements, qui affectent l’expression de certains gènes, sans modifier la séquence d’ADN, interfèrent avec le fonctionnement des systèmes régulant la réponse au stress. À long terme, l’adversité durant l’enfance, en induisant ces changements épigénétiques, prédispose certains individus à développer des problèmes de santé mentale à l’âge adulte. Ce chapitre traite de l’impact épigénétique de l’adversité au cours du jeune âge et de ses conséquences comportementales sur la santé mentale.
Abstract
Adversity during childhood has for long been known to increase the risk of developing mental health problems in adulthood. Yet, it is only recently that epigenetic mechanisms have been identified as representing an interface on which the environment acts upon to induce behavioral changes. These changes affecting the expression of certain genes, without however modifying DNA sequences, particularly interfere with the functioning of systems regulating response to stress. In the long term, adversity during childhood, by inducing these epigenetic changes, predisposes some individuals in developing mental health problems in adulthood. This article examines the epigenetic impact of adversity during childhood and its behavioral consequences on mental health.
Appendices
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